đź—¨ About Me

I am a full-time Lab Specialist at the Center for Public Health Genomics in University of Virginia School of Medicine advised by Prof. Chongzhi Zang.

Previously, I received my Master’s degree in Computer Science from Johns Hopkins University and Bachelor’s degree in Computer Science from Wenzhou-Kean University. I did my master thesis advised by Prof. Kimia Ghobadi at Johns Hopkins on multi-agent simulation. I was fortunate to work with Prof. Aloysius Wong’s group where I first stepped into the field of bioinformatics. In addition, I developed a deep learning model for RNA-ligand affinity prediction with Prof. Yanjun Li at UFL and later participated in developing a single-cell foundation model in Prof. Xiaojie Qiu’s Lab at Stanford.

I mainly work on the intersection of machine learning and biology in a broad scope. I am interested in foundation models and LLMs for science including single-cell, RNA, and protein, and how to use them to discover and interpret the biological mechanism.

Research Interests:

  • Single-cell Multi-omics
  • Deep learning for Cancer Biology and Chemical Biology
  • AI for Drug Discovery

đź“– Educations

  • 2022.08 - 2023.12, Master of Science in Engineering, Computer Science. Johns Hopkins University. Baltimore, MD
  • 2018.08 - 2022.05, Bachelor of Science, Computer Science. Wenzhou-Kean University. Wenzhou, China

đź“° News

đź“ť Publications

ALIFE 2023
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Simulating Disease Spread During Disaster Scenarios

Shiyu Jiang, Heejoong Kim, Fabio Henrique Tanaka, Claus Aranha, Anna Bogdanova, Kimia Ghobadi, Anton Dahbura. The International Conference on Artificial Life, 2023.

Code

Bioinformatics
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HNOXPred: a web tool for the prediction of gas-sensing H-NOX proteins from amino acid sequence

Shiyu Jiang, Hemn Barzan Abdalla, Chuyun Bi, Yi Zhu, Xuechen Tian, Yixin Yang, Aloysius Wong. Bioinformatics, 2022

Website | Code

IJCNN 2021
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Deblur-yolo: Real-time object detection with efficient blind motion deblurring

Shen Zheng, Yuxiong Wu, Shiyu Jiang, Changjie Lu, Gaurav Gupta. International Joint Conference on Neural Networks, 2021

🧑‍💻 Research Experience

  • 2023.06 - Present, Lab Specialist, Chongzhi Zang Lab, Center for Public Health Genomics, University of Virginia, Charlottesville, VA.
  • 2023.08 - Present, Remote Research Assistant, Xiaojie Qiu Lab, Stanford School of Medicine, Remote.
  • 2023.06 - 2024.03, Remote Research Assistant, Yanjun Li Lab, University of Florida College of Pharmacy, Remote.
  • 2022.09 - 2023.12, Postgraduate Research Assistant, Kimia Ghobadi Lab, Johns Hopkins Withing School of Engineering, Baltimore, MD.
  • 2021.08 - 2022.06, Undergraduate Research Assistant, Aloysius Wong Lab, Wenzhou-Kean University Department of Biology, Wenzhou, China.

🧑‍💻 Professional Experience

🔨 Tools

Model

  • Koudou: an agent-based model that simulates the infectious diseases.

Web server

  • HNOXPred (Prediction of Heme-Nitric oxide/OXygen domains): a web server that predicts gas-sensing H-NOX proteins from amino acid sequences.

Python Package

  • SICER 2.0 (Spatial-clustering Identification of ChIP-Enriched Regions): a ChIP-Seq broad peak calling data analysis method.

🌎 Miscellaneous

Soccer (Visca Barça), Gym, Table tennis, Piano, Travel, etc.